After half a century mitochondrial calcium in- and efflux …

Mitochondrial Ca (2+) uptake and release play a fundamental role in the control of different physiological processes, such as cytoplasmic Ca (2+) signalling, ATP …

Molecular machinery regulating mitochondrial calcium …

One of the key determinants that calibrate both cellular energetics and survival functions is mitochondrial calcium (Ca 2+) dynamics. Mitochondrial Ca 2+ …

After half a century mitochondrial calcium in- and efflux …

Keywords: calcium; MCU; MICU1; mitochondria; NCLX Introduction All membrane enclosed organelles (with the notable excep-tion of nucleus and peroxisomes that …

Mitochondrial Calcium Handling in Physiology and Disease

This chapter is primarily focused on the role of mitochondria in cellular Ca 2+ handling. Indeed, many subcellular compartments, including mitochondria, are key …

Structure and mechanism of the mitochondrial Ca2

Here, we report cryo-EM structures of human mitochondrial calcium uniporter holocomplex in inhibited and Ca 2+-activated states. These structures define the architecture of this …

Mitochondria as sensors and regulators of calcium …

During the past two decades calcium (Ca2+) accumulation in energized mitochondria has emerged as a biological process of utmost physiological relevance.

Molecular machinery regulating mitochondrial calcium …

Mitochondrial calcium (Ca 2+) homeostasis regulates aerobic metabolism, cell survival, cellular Ca 2+ signaling and mitochondrial reactive oxygen species (mROS) …

The machineries, regulation and cellular functions of …

Calcium ions (Ca 2+) are ubiquitous second messengers that translate information delivered by extracellular and intracellular signals into an intracellular effect.

The machineries, regulation and cellular functions of …

Calcium ions (Ca2+) are some of the most versatile signalling molecules, and they have many physiological functions, prominently including muscle contraction, …

Molecular machinery regulating mitochondrial calcium …

Mitochondria play vital role in regulating the cellular energetics and metabolism. Further, it is a signaling hub for cell survival and apoptotic pathways. One of the key determinants …

LLINI est une entreprise leader et pionnière avec le niveau international le plus avancé en matière de R&D.

Des produits
Contactez-nous

Adresse : No.416 Jianye Road, South Jinqiao Area, Pudong, Shanghai, China

Téléphone : 0086-21-58386256

E-mail : [email protected]

Droit d'auteur et copie ; 2024.LLINI Tous droits réservés.plan du site