clivage naturel

The Emergence of the Spike Furin Cleavage Site in SARS-CoV-2

In some CoVs, the spike protein is effectively processed at furin cleavage sites (FCS; minimal motif of R-X-X-R) that can occur at the S1/S2 boundary, which plays …

The origin of SARS-CoV-2 furin cleavage site remains a mystery

A new study on the Preprints server discusses the origin of the furin cleavage site on the SARS-CoV-2 spike protein, which is responsible for the virus's …

Loss of furin cleavage site attenuates SARS-CoV-2 …

Nature - Experimental deletion of the furin cleavage site of the SARS-CoV-2 spike protein highlights an important role for this site in infection and the need to consider this site when...

Furin cleavage sites naturally occur in coronaviruses

The spike protein of the Middle East respiratory syndrome coronavirus (MERS-CoV) was discovered to be more effectively cleaved by another protease, furin ( …

Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

Overall, our work highlights the importance of this key motif in SARS-CoV-2 infection and pathogenesis. Article summary: A deletion of the furin cleavage site in …

Définitions : clivage

clivage. nom masculin. (de cliver) 1. Fracture selon certains plans d'orientation précise, particulière à certains minéraux, cristaux et roches. 2. Séparation, différenciation, …

clivage de cliver

Le clivage est l'une des manifestations de l'anisotropie discontinue des cristaux. Il se fait en général le long des plans de la structure cristalline pour lesquels il y a un nombre …

Oxidative cleavage and ammoxidation of organosulfur …

Nature Communications - The cleavage and functionalization of C-S bonds has become a hot topic. Here the authors report a novel and efficient protocol that …

Loss of Furin Cleavage Site Attenuates SARS-CoV-2 …

Similarly, altered antibody neutralization profiles indicate a critical need to survey this mutation in analysis of SARS-CoV-2 treatments and vaccines. Overall, the work …

The furin cleavage site in the SARS-CoV-2 spike …

Nature Microbiology - Efficient transmission of SARS-CoV-2 among infected ferrets requires a functional furin cleavage site in the …